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ADME properties

26

Description

Drug metabolism and pharmacokinetics (DMPK) is a scientific discipline related to safety assessment of drug development, and is becoming a core discipline of drug discovery and development. DMPK is the study of drug disposition process in the organism. It describes the process of absorption, distribution, metabolism and excretion (ADME) using mathematical and dynamic models and combines the exposure of drugs in blood circulation and target organs with clinical manifestations (pharmacodynamics and toxic side effects).

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