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ExoMAb methods



Exosomes are natural carriers of proteins, lipids, DNA, miRNA, and IncRNA. There is increasing interest in manipulating the protein composition of exosomes using the exosome display technology. This technology is very versatile since soluble, membrane-bound, trans-membrane or multimeric antigens that are not naturally found on exosomes can now be efficiently expressed at their surface in a native conformation. To drive the development of membrane protein therapeutics, Creative Biolabs is utilizing the exosome display technology for generation and isolation of antibodies against different drug targets, notably including those difficult targets such as the G-protein coupled receptors (GPCRs).

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